Nodal signalling molecules are crucial for key steps in embryonic development. The function of these TGFβ family ligands are largely conserved across vertebrates. Yet there remain many unanswered questions on how these molecules and the genes they regulate control embryonic tissue patterning. Read more about it in this extensive review by Alex and two talented PhD students from the lab: Jake and Mireia!
New review on Nodal signalling in embryonic development!