Congratulations to Yinan and the team for their paper on embryogenesis in 4D!

Yinan and her team have generated a huge dataset capturing how gene expression changes across time and space in zebrafish embryos. To do this in the thick zebrafish embryo samples they developed a new method: whole-embryo imaging platform using multiplexed error-robust fluorescent in situ hybridization (weMERFISH). Moreover, they could map the expression of thousands of unmeasured genes through computational methods. Allowing the most expansive and comprehensive transcriptional atlas of embryo development yet. This exciting work was published in Science. Read more about the work here and the paper itself here. This is a huge collaborative project with valuable contributions from many scientists. Learn more about the collaborative labs: Bogdan Bintu, Guoqiang Yu, Susan Mango, and Ahilya Sawh.

See also a companion paper on mapping lineages by the lab of Guiqiang Yu with contributions from Joaquin, Yinan and Alex.