Cellular differentiation - where stem cells become specialised cell types, for example, the differentiation of embryonic stem cells to functional cell types like neurons or liver cells, is not completely understood. Yiqun’s study presents a novel approach for identifying functional gene modules and demonstrates how transcription factors can control both general and specialised cell functions.
Congratulations to Yiqun and the other collaborators, which includes the lab of Jeff Farrell - a former lab member now at NIH!
Read the paper here